A New Era in Psoriasis and Psoriatic Arthritis Therapy: Drugs with New Mechanism of Action and the Option for the use Biosimilars

A new era in psoriasis and psoriatic arthritis therapy: new mechanisms of action and the introduction of biogeneric drugs.

The use of biosimilar drugs in psoriasis: a position paper.

-The development of biologic therapy has substantially improved the treatment of psoriasis and psoriatic arthritis. At the same time, the elevated cost of biologics has prompted debate on the economic sustainability of the public health system. -As patents expire for biologics, business interests and the high capacity of today’s biotechnology industry have encouraged laboratories to develop new...

Depression and quality of life in psoriasis and psoriatic arthritis patients

ackground: Psoriasis is a chronic hyperproliferative disease of the skin, scalp, nails, and joints that affects 2% of the general population. One of the extracutaneous manifestations of psoriasis is psoriatic arthritis which occurs in 25–34% of the psoriasis cases. This type of inflammatory arthritis is characterized by pain, swelling, and tenderness around the joints, and may adversely a...

Autoimmunogenicity during anti-TNF therapy in patients with psoriasis and psoriatic arthritis

INTRODUCTION The tumor necrosis factor (TNF-α) was initially described as lymphotoxin or cachectin. The discovery of therapies blocking the action of TNF-α, in 1988, started a new era in the therapy. One of often reported adverse effects related to the use of TNF-α antagonists is induction of the formation of autologous antibodies and antibodies neutralizing anti-TNF drugs. The development of a...

PSORIATIC ARTHRITIS IN 300 PSORIATIC PATIENTS IN IMA M REZA HO SPITAL, MASH H AD UNIVERSITY OF MEDICAL SCIENCES

In order to study the prevalence of psoriatic arthritis in Imam Reza Hospital and determine the effects of factors like age, sex, familial history, type of skin involvement, nail involvement and duration of disease on psoriatic arthritis, 300 psoriatic patients over a period of 4 years were admitted and examined in the Department of Dermatology and Rheumatology in Imam Reza Teaching Hospita...